Semaglutide: From Peptide Engineering to FDA and Health Canada Milestones
A scientific timeline of semaglutide, focusing on peptide engineering, receptor pharmacology, pivotal evidence and regulatory milestones.
North Specs Labs
NORTH SPECS RESEARCH PEPTIDES LABS
Tirzepatide and Dual GIP/GLP-1 Receptor Agonism
A mechanistic and evidence-led review of tirzepatide as a dual GIP and GLP-1 receptor agonist, with guidance for laboratory assay design.
Retatrutide: What Triple-Agonist Research Shows So Far
A focused review of retatrutide as a GIP, GLP-1 and glucagon receptor agonist, from phase 1b and phase 2 trials to structural biology.
Retatrutide, Tirzepatide and Semaglutide: How to Compare the Research
A method-first comparison of semaglutide, tirzepatide and retatrutide that separates receptor design, trial populations and regulatory status.
GIP Receptor Pharmacology: Why the Experimental Context Matters
A guide to GIP receptor biology, agonism and antagonism, with emphasis on species, receptor expression and matched functional assays.
Incretin Research: GLP-1, GIP and the Move to Multi-Receptor Agonists
How incretin biology went from an obscure gut-hormone observation to the most productive area of metabolic peptide research, and what the single, dual and triple agonist literature actually shows.