How Research Peptides Are Made: Solid-Phase Synthesis, Purification and Cost
Understanding how a peptide is built explains why some sequences cost ten times more than others at the same purity, and where…
Read briefingResearch notes & methods
The North Specs research library
Long-form educational briefings on peptide research, laboratory methodology and the evolving research landscape across Canada, the United States and Europe.
Educational material for qualified researchers. Nothing in this library is medical advice or a use protocol for humans or animals.
All briefingsBioregulation & SignallingGH SecretagoguesLongevity ResearchMetabolic ResearchMethodologyNeuro & Cognitive
Why Your Peptide Assay Disagrees: Purity, Counter-Ions and Reproducibility
Most irreproducible peptide results are not biology. They are material. A practical guide to the variables that make the same nominal compound…
Read briefingThymosin Alpha-1: Immune Modulation Research
A thymic peptide with an unusually long clinical history, approvals in some jurisdictions and not others, and a mechanism centred on dendritic…
Read briefingMelanocortin Peptides: Receptor Subtypes, Selectivity and the PT-141 Story
Five receptor subtypes controlling pigmentation, energy balance, inflammation and sexual function. Selectivity is the whole problem, and the reason two closely related…
Read briefingSemax and Selank: Regulatory Peptides in Neuroscience Research
Two peptides derived from endogenous human sequences, developed in Russia, studied for effects on neurotrophic signalling and stress response. What the literature…
Read briefingGrowth Hormone Secretagogues: GHRH Analogues Versus Ghrelin Mimetics
Two mechanistically distinct receptor systems both raise growth hormone output. Understanding the difference is the key to designing interpretable experiments on the…
Read briefingGHK-Cu: Copper Peptide Research in Wound Healing and Skin Biology
A naturally occurring tripeptide with genuine copper coordination chemistry and one of the better-characterised mechanisms in the tissue-repair peptide field.
Read briefingEpithalon and the Peptide Bioregulator Tradition
A research tradition that developed largely outside Western literature, its central claims about telomerase and pineal function, and the reasons independent assessment…
Read briefingMitochondrial-Derived Peptides: MOTS-c, Humanin and the Microprotein Field
Short open reading frames in mitochondrial DNA encode peptides that appear to signal to the nucleus. What the evidence supports, and what…
Read briefingThe Peptide Research Landscape in Europe
EMA pathways, Horizon Europe funding, REACH obligations, and the national clusters where European peptide science is concentrated.
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